GRAN RESERVA revolves around two families of Rioja winemakers. The Cortázar consider wine as a lucrative business. For Reverte the vine and the earth are a way of life. In spite of their rivalry, both families live in a balance that is broken drastically when someone tries to assassinate Miguel, the first-born of the Cortázar. Although the young man survives, he loses his memory, and that causes the world of one and others to change forever. Between the powerful Cortázar and the Reverte fighters there is much pain to overcome and hatreds that have increased. The patriarch of the Cortes is betrayed by his young son, although he believes he has the support of his eldest son, Miguel, to prosper at any cost. Meanwhile, Raúl Cortázar integrates into the Reverte clan with an appearance of good intentions and a relationship with Lucia. After getting rid of don Vicente of the family home and the wineries, the Cortázar live more calmly. But that tranquility will not last too long: old accounts of the past, a sudden death, the less expected return and the arrival of a new member of the family will check the Cortazar. For their part, the Reverte have managed to collect enough money to pay the price and get Lucía out of jail. This is a company in ruins because of the embezzlement of Raúl Cortázar. In spite of everything, the young woman does not think to stop until saving the warehouses of its family and to give back to the rival family all the damage that they have caused to them in the last years.